Parallelization of General-Linkage Analysis Problems
نویسندگان
چکیده
منابع مشابه
Parallelization of general-linkage analysis problems.
We describe a parallel implementation of a genetic-linkage analysis program that achieves good speed improvement, even for analyses on a single pedigree and with a single starting recombination fraction vector. Our parallel implementation has been run on three different platforms: an Ethernet network of workstations, a higher-bandwidth asynchronous transfer mode (ATM) network of workstations, a...
متن کاملIntegrating parallelization strategies for linkage analysis.
We describe a second parallel implementation of the ILINK program from the LINKAGE package that improves on our previous implementation. To improve running time we integrated the strategy of parallel estimation of the gradient at a candidate recombination fraction vector with a previously implemented strategy for evaluating in parallel the likelihood at one vector. We also integrated an adaptiv...
متن کاملPowerful regression-based quantitative-trait linkage analysis of general pedigrees.
We present a new method of quantitative-trait linkage analysis that combines the simplicity and robustness of regression-based methods and the generality and greater power of variance-components models. The new method is based on a regression of estimated identity-by-descent (IBD) sharing between relative pairs on the squared sums and squared differences of trait values of the relative pairs. T...
متن کاملA General Boundary Element Formulation for The Analysis of Viscoelastic Problems
The analysis of viscoelastic materials is one of the most important subjects in engineering structures. Several works have been so far made for the integral equation methods to viscoelastic problems. From the basic assumptions of viscoelastic constitutive equations and weighted residual techniques, a simple but effective Boundary Element (BE) formulation is developed for the Kelvin viscoelastic...
متن کاملMultipoint quantitative-trait linkage analysis in general pedigrees.
Multipoint linkage analysis of quantitative-trait loci (QTLs) has previously been restricted to sibships and small pedigrees. In this article, we show how variance-component linkage methods can be used in pedigrees of arbitrary size and complexity, and we develop a general framework for multipoint identity-by-descent (IBD) probability calculations. We extend the sib-pair multipoint mapping appr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Heredity
سال: 1994
ISSN: 1423-0062,0001-5652
DOI: 10.1159/000154205